Press release

AB-Biotics launches the first probiotic specifically designed against caries, gingivitis and halitosis
Barcelona (Spain), March.- The Spanish biotech company AB-Biotics, listed on the Spanish Alternative Stock Market (MAB), has launched the first probiotic specifically designed to fight the oral pathogens causing caries, gingivitis and halitosis or bad breath, very common oral health diseases which can affect up to 99% population.
The formula, called AB-Dentis, contains two strains (Lactobacillus plantarum and Lactobacillus brevis) which have bactericidal activity against the most common oral pathogens without producing important amounts of acids, preserving the teeth.

AB-Dentis can be administered in products like chewing gums, toothpastes and dentifrices, denture products or mouth sprays. To bring this probiotic to the market, AB-Biotics has signed a distribution agreement with the Danish firm CMS Dental: this company will have the rights to market AB-Dentis worldwide until 2022. CMS Dental has 25 years’ experience in the development of dental products and will present AB-Dentis during the International Dental Supply (IDS), the largest exhibition of the sector, to be held in Cologne (Germany) in 12th-16th March with more than 1,900 exhibitors from 55 countries.

A problem on everyone's mouth

The mouth contains hundreds of types of bacteria: in normal conditions these bacteria work
as a natural defense system for the mouth, but some factors (inadequate oral higiene, illness, stress, poor diets…) can disrupt this protective oral balance and allow bad bacteria to cause poor gum health, plaque build up and bad breath.

Using in vitro studies, AB-Biotics’ team selected from more than 550 wild strains those who had higher antibacterial activity against pathogens causing caries, gingivitis and halitosis, common disorders in large populations. The strains selected for the AB-Dentis’ formula colonize the mouth adhering to teeth, gums and tongue to prevent the introduction of pathogens and displace those already in place.

Gingivitis is an inflammation of the gum. It’s estimated that up to 90% population has suffered gingivitis at some point of their life, and some factors raise this risk: general illness, poor dental hygiene, uncontrolled diabetes or pregnancy. In fact, between 50%-70% of women develop gingivitis sometime during their pregnancy. Gingivitis may evolve into periodontitis which is a degenerative process of the tissue that surrounds the teeth. It involves inflammation and infection that destroys the tissues that support the teeth, including the gums, the periodontal ligaments, and the tooth sockets. In the industrialised countries 30% of the grown up population suffer from periodontitis making it the biggest single cause of loss of teeth.

Halitosis or bad breath is produced by specific genus of the oral microbiota. It’s estimated that 50% of population suffer halitosis in some degree. Caries is a biofilm (plaque)-induced acid demineralization of enamel or dentin, mediated by saliva. Dental caries is still a major oral health problema in most industrialized countries, affecting 60-90% of schoolchildren and the vast majority of adults according to World Health Organization.
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