Press release

Improvement of fertility in women with polycystic ovary syndrome. Biosearch Life's new clinical trial and patent.
Caronositol DCI
Biosearch Life has applied for a patent based on a new method for increasing the rate of embryo implantation in polycystic ovary syndrome, as well as for the treatment of symptoms of the disease: Method for increasing embryo implantation rates in a female subject suffering polycystic ovary syndrome ".
This patent is based on the results obtained in a multicentre, randomized, controlled and double-blind clinical trial, the goal of which was to compare the effect of two proportions of myoinositol / D-chiro-inositol in parameters related to fertility in women with polycystic ovary syndrome. The main researcher in the study is Dr. Nicolás Mendoza Ladrón de Guevara, from the Department of Obstetrics and Gynaecology at the University of Granada.

Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disease where gynaecological disorders coexist with metabolic problems. It is the most prevalent endocrinopathy in women, affecting 4-8% of those who are of childbearing age and may even reach 15% if we take the Rotterdam 2003 criteria into account.

Both D-chiro-inositol and myoinositol are two natural substances that have been shown to improve ovarian function and metabolism in women with polycystic ovarian syndrome. In previous studies, the combined MI / DCI therapy was effective in the treatment of infertility, in a 40: 1 ratio. The new combination used by Biosearch Life, with a greater amount of DCI (Caronositol), has proven to be more effective, achieving a pregnancy rate of up to three times higher.

This study has been carried out within the framework of the CIEN METASIN Strategic Project: Research, Development and Innovation in new multifunctional foods for Metabolic Syndrome, funded by the Centre for Industrial Technological Development (CDTI) in the 2015 call and led by Biosearch Life. The company's strategy in this project is the development of innovative products with sufficient scientific evidence to support their use in the treatment and/or prevention of the different pathologies related to metabolic syndrome, such as PCOS.
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