Fundación Medina
Contact information
Fundación Medina (Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucia)
Olga Genilloud, Directora Científica
Edificio Desarrollo Farmacéutico. Avda. Conocimiento 3, Parque Tecnológico Ciencias de la Salud
Granada
Granada
958993965
958846710
Areas of activities
- A. Health Biotechnology
- Areas of activity
- Biodrugs
- Cell cultures
- Drug discovery
- Screening
- Therapeutic areas
- Genetic and rare diseases
- Infectious diseases
- Immunology
- Oncology
- Central nervous system
- B. Agrifood Biotechnology
- Agriculture / veterinary / environmental
- Biologic control (plagues..) and bioestimulants of crops
- Animal health / Veterinary
- C. Industrial Biotechnology
- Waste valorisation
- D. Services
- R&D services
- Metabolomics
- CRO / CMO / SMO
- Professional services
- Consultancy
- Training and spreading
Commissions
Fundación MEDINA is a non-profit public-private partnership between Merck Sharp and Dohme de España S.A., the Junta de Andalucía and the University of Granada, to discover innovative compounds and therapies for unmet medical needs.
Research activities at MEDINA are focused on:
I.Discovery of new compounds and therapies as new leads for drug development.
II. Contract Research Services: High throughput screening services for lead discovery, ADME/TOX, bioanalysis and metabolomics
Products and services
- New leads from microbial natural products in therapeutic areas with unmet medical needs.
- License of natural product libraries
- Drug discovery sreening platform
- Highly automated screening services, including High Content Imaging.
- Safety, adverse drug metabolism (ADME/TOX)and toxicity platform of drug candidates in development:
- Cardiotoxicity: ion channels assays (hERG, Cav1.2, Nav1.5)
- Drug metabolism assays(CYP inhibition and induction, drug stability and metabolite profiling)
- Cytotoxicity
- Genotoxicity (AMES Test)
- Turbidimetry and solubility
Off-target interactions(neurotransmisor receptors, PPARs)
- Bioanalysis and metabolomics (High resolution MS)
Areas of interest for future collaborations
- Discovery of novel therapeutics from microbial natural products collections in: infectious diseases (including tuberculosis and parasitic diseases), oncology, immunoregulation and rare diseases.
- Study of potential cardiovascular and neuronal safety risks, and drug-drug interactions of new leads in early stages of the drug-discovery process.
- Metabolomic analysis and identification of metabolism biomarkers
Biotech Sanitaria
| Product / Service | Type | Therapeutic area | Development phase |
|---|---|---|---|
| MDN-088 | Biodrugs/ Drugs | Oncología | R&D |
| MDN-0090 | Biodrugs/ Drugs | Oncología | R&D |
| MDN-005 | Biodrugs/ Drugs | Sistema nervioso central, Desórdenes musculoesqueléticos | R&D |
| Product / Service | Type | Development phase |
|---|---|---|
| High throughput screening platform for drug discovery | Screening/Drug Discovery | Clinical Validation |
| Microbial Natural Product Libraries | Screening/Drug Discovery | Clinical Validation |
| Screening Cell lines & Animal Models | Screening/Drug Discovery | Preclinical |
| Mass spectrometry metabolomics | Enabling Technologies, Screening/Drug Discovery | R&D |
| Preclinical Safety Platform | CRO, CMO | Clinical Validation |
| Bioanalytical Platform | CRO, CMO | Clinical Validation |
| Chemical Isolation & Structural Elucidation of natural products | CRO, CMO | Clinical Validation |
| Microbial and Mammalian cell culturing | CRO, CMO | Clinical Validation |
| Product / Service | Type | Therapeutic area | Development phase |
|---|---|---|---|
| Metabolomics Biomarkers Identification Platform | Biomarkers, Diagnostic | Oncología, Enfermedades infecciosas, Trastornos metabólicos / Endocrinología | Clinical Validation |
| Biomarkers Platform | Biomarkers, Diagnostic | Oncología | Clinical Validation |
Biotech Agroalimentaria
| Product / Service | Aplication | Development phase |
|---|---|---|
| MEDScreen platform | Agrofood industry. | Validation |
| MEDmicro platform | Agrofood industry. | Validation |
| MEDiscovery platform | BEA provides services to companies and research institutions, in order to facilitate the implementation of initiatives and projects related to research and industrial developments in the field of cyanobacteria, microalgae and macroalgae biotechnology. | R&D |
| MEDchemistry platform | Agrofood industry. | Validation |