Nostrum Biodiscovery

Contact information
- A. Health Biotechnology
- Areas of activity
- Drug discovery
- C. Industrial Biotechnology
- Enzymes
- D. Services
- R&D services
- Bioinformatics
- CRO / CMO / SMO
- Professional services
- Consultancy
Nostrum Biodiscovery (NBD) is an in silico company specialized in drug discovery through the combination of computational tools. NBD accelerates hit finding and hit-to-lead (H2L) projects with the use of its in silico platforms. Regarding hit finding, NBD has built the PELE platform for virtual screening with commercial compounds (~ 8M) as well as with proprietary compounds (~ 1M). This platform allows to find new chemical entities saving time and resources. With respect to H2L, NBD executes Molecular Dynamics (MD) and Monte Carlo (MC) simulations to adjust and optimize the activities of the compounds. Currently, PELE has already been used in several industrial and academic projects, which include the discovery of active molecules against many types of therapeutic targets.
In addition, PELE technology has been adapted to evolve enzymes to improve their performance such as stability in extreme pH environments, activity at high temperature, etc. These enzymes cover different industrial fields such as biotechnology, detergents, food, biofuels...
Finally, NBD has its own portfolio of drug discovery projects through collaborations with academic groups such as the University of Barcelona (UB), the Institute for Research in Biomedicine of Barcelona (IRB), the University of Salamanca or the Vall Hebron Institute of Research, among others.
The company is the first joint spin-off of the Barcelona Supercomputing Center (BSC) and the IRB and also has the participation of the University of Barcelona, ICREA and the Marcelino Botín Foundation. The entrepreneurs are Professor Modesto Orozco (UB, IRB), Professor Víctor Guallar (BSC) and Dr. Robert Soliva.
Servicios:
- RATIONAL MOLECULAR DESIGN
- ENZYME ENGINEERING
Software as a Service:
- PELE SIMULATION PLATFORM
- ED/MD SUITE SIMULATION
- ChemistriX
- Drug Discovery
- Enzyme Engineering