Junior Scientist

OneChain Immunotherapeutics S.L (OCI) is a clinical stage spin-off company from Fundación Josep Carreras with investment by Invivo Ventures, Clave Capital, Nara Capital and CDTI-Innvierte (Ministerio de Industria). Our mission is to improve people’s health by advancing our clinical and preclinical pipeline of CAR T-cells against various cancers. OCI is growing rapidly and is about to expand to a new laboratory in the Barcelona Scientific Park (PCB). For more information, please visit https://www.onechaintx.com

Junior Scientist:

Role and functions We are looking a strongly motivated, dynamic and exceptional researcher with a PhD in life sciences and experience with in vivo models in oncology. You will have a key role in advancing various products in our promising preclinical CAR-T pipeline towards clinical trials.

The candidate will:

• Design and take responsibility for all animal work.
• Set up our in-house animal facility at PCB.
• Collaborate effectively with an extensive network of scientists and with the execution of several projects within the company.
• Coordinate with CROs/collaborators for animal work done externally.
• Work in coordination with the Research Director.
• Develop cutting-edge cellular tools in the field of new CAR-T and autologous and allogeneic therapies in order to implement it use, culture conditions and scale-up feasibility at the pre-clinical and clinical stages.
• Conduct independently in vitro and in vivo immunological analysis.

Qualification required:

• PhD holders with reasonable experience in industry, CROs or academia in scientific areas related with cancer animal models.
• An up to date “experimental animal certification” (A/B/C/D functions ECC 566 / 2015)

Experience required:

• Scientific track record demonstrated with publications or patents. 
• Strong knowledge of experimentation working with animal models and/or immunodeficient mice and technical skills in general cell culture and molecular biology.
• Experience in cell biology, molecular oncology, hematology and immunology

Desirable experience. The following experience specifications constitute a qualification bonus:

• Immuno-oncology and/or immunology.
• Flow cytometry.
• General cell culture of cell lines and primary cells.
• Handling of primary human blood samples.
• Viral vector production.
• In vitro and in vivo preclinical work for clinical trials, regulatory IMPD applications.
• Basic understanding of GMP requirements for Cell and Gene Therapy

Key Competencies:

• Excellent oral and written communications skills.
• Independence, leadership, technical troubleshooting.
• Excellent interpersonal skills and the ability to work as part of a team.
• Capacity to work under deadlines pressure to meet company’s goals.

English level:

• Fluent (written and oral).

Salary:

• Competitive salary plus bonus based on qualifications and consistent with the company’s pay scales (Junior Scientist).

Condition:

• An open-ended contract.
• Selected candidates will receive specific training in those areas that require a higher expertise.
• Target start date is March-April 2024.

Location:

• Parc Científic de Barcelona (PCB): https://www.pcb.ub.edu/en